Petfood Industry - July 2019 - 36

36 | www.PetfoodIndustry.com

➥INGREDIENT ISSUES
to have very limited connection.
Oral studies have been conducted
with mixed results for chronic
consumption and no oral toxicity
for acute consumption in murine
species has been observed.
Immune challenge studies
have provided mixed results with
some suggestion that nanoparticles may be able to accumulate in
the Peyer's patches and cross the
lamina propria of the intestinal
lining through the enterocytes
and reach the blood stream via
the lymphatic system where they
could be identified in trace quantities in the liver, spleen and kidney.
To date, there are no dog or
cat studies evaluating safety or
efficacy, and most of the work is
extrapolated from rat or mouse
research for human applications.
Much of that work is well beyond
super-physiological doses and not
evaluated in food-model systems.

So, extrapolation is fraught with
great potential for error; however,
that has not stopped France from
placing a one-year moratorium
on the use of titanium dioxide
starting in 2020. The rationale is
that it will allow for additional
information gathering to demonstrate safety for oral ingestion.
Their actions go outside the directive of the European Food Safety
Authority (EFSA). No record of
action by U.S. Food and Drug
Administration (FDA) has been
noted.

Uses of titanium
dioxide in pet food
products
Beyond coloring, titanium
dioxide may hold benefit as a
marker in assessment of energy
digestion in companion animals
as a recent paper suggests it was
equally effective for this purpose

to chromic oxide. In this study, the
authors compared the quantitative collection method and the
chromic oxide indicator method to
titanium dioxide. All other procedures were consistent with those
described by the Association of
American Feed Control Officials
(AAFCO) 2019 for determination of food metabolizable energy
protocols. In their work, they
showed that the titanium dioxide
was highly correlated to the standard chromic oxide procedure and
each provided a better estimate
than quantitative collection.
If titanium and chromium are
essentially the same, then why
would we consider changing? For
a couple of reasons ... titanium
dioxide is an approved food additive, it is readily available through
standard ingredient procurement
channels and the analysis of titanium is more straightforward.

July 2019

Industry


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Petfood Industry - July 2019

Table of Contents for the Digital Edition of Petfood Industry - July 2019

Petfood Industry - July 2019
Contents
Should consumer demands always dictate pet food’s path?
Speaking of…
News and Calendar
Lucky & Prince: Human-grade pet food at accessible prices
3 considerations of pet food facility safety
E-commerce: A growing pet product purchasing channel
5 free-from claims top sales in US pet food market
Guide to Petfood Forum China 2019
Pet chew net content declarations: Is count sufficient?
Titanium dioxide: A whitener with broad application
Taking a page from pet supplements
New Products
Marketplace
Advertiser’s Index
Petfood Industry - July 2019 - CT1
Petfood Industry - July 2019 - CT2
Petfood Industry - July 2019 - Petfood Industry - July 2019
Petfood Industry - July 2019 - Cover1a
Petfood Industry - July 2019 - Cover1b
Petfood Industry - July 2019 - Cover2
Petfood Industry - July 2019 - 1
Petfood Industry - July 2019 - Contents
Petfood Industry - July 2019 - 3
Petfood Industry - July 2019 - Should consumer demands always dictate pet food’s path?
Petfood Industry - July 2019 - 5
Petfood Industry - July 2019 - Speaking of…
Petfood Industry - July 2019 - 7
Petfood Industry - July 2019 - News and Calendar
Petfood Industry - July 2019 - 9
Petfood Industry - July 2019 - Lucky & Prince: Human-grade pet food at accessible prices
Petfood Industry - July 2019 - 11
Petfood Industry - July 2019 - 12
Petfood Industry - July 2019 - 13
Petfood Industry - July 2019 - 3 considerations of pet food facility safety
Petfood Industry - July 2019 - 15
Petfood Industry - July 2019 - 16
Petfood Industry - July 2019 - 17
Petfood Industry - July 2019 - E-commerce: A growing pet product purchasing channel
Petfood Industry - July 2019 - 19
Petfood Industry - July 2019 - 20
Petfood Industry - July 2019 - 21
Petfood Industry - July 2019 - 5 free-from claims top sales in US pet food market
Petfood Industry - July 2019 - 23
Petfood Industry - July 2019 - 24
Petfood Industry - July 2019 - 25
Petfood Industry - July 2019 - Guide to Petfood Forum China 2019
Petfood Industry - July 2019 - 27
Petfood Industry - July 2019 - 28
Petfood Industry - July 2019 - 29
Petfood Industry - July 2019 - Pet chew net content declarations: Is count sufficient?
Petfood Industry - July 2019 - 31
Petfood Industry - July 2019 - 32
Petfood Industry - July 2019 - 33
Petfood Industry - July 2019 - Titanium dioxide: A whitener with broad application
Petfood Industry - July 2019 - 35
Petfood Industry - July 2019 - 36
Petfood Industry - July 2019 - 37
Petfood Industry - July 2019 - Taking a page from pet supplements
Petfood Industry - July 2019 - 39
Petfood Industry - July 2019 - 40
Petfood Industry - July 2019 - New Products
Petfood Industry - July 2019 - 42
Petfood Industry - July 2019 - 43
Petfood Industry - July 2019 - 44
Petfood Industry - July 2019 - 45
Petfood Industry - July 2019 - 46
Petfood Industry - July 2019 - 47
Petfood Industry - July 2019 - Marketplace
Petfood Industry - July 2019 - 49
Petfood Industry - July 2019 - Advertiser’s Index
Petfood Industry - July 2019 - Cover3
Petfood Industry - July 2019 - Cover4
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